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Understanding TMG (Trimethylglycine)
TMG is a naturally occurring compound found in foods such as beets, spinach, and quinoa. In the body, it plays a central role in transferring methyl groups — small chemical units required for a wide range of cellular reactions.
- DNA expression and repair
- Neurotransmitter synthesis
- Hormone metabolism
- Cardiovascular function
- Cellular energy production
- Healthy aging processes
As we age or experience nutritional stress, the demand on methylation pathways may increase. Providing reliable methyl donors can help maintain balance across these systems.
Liposomal Delivery
for Enhanced Uptake
Standard forms of TMG may be partially degraded during digestion. This formula uses sunflower-derived phospholipids to encapsulate TMG, helping protect it as it passes through the digestive tract.
Because phospholipids resemble cell membranes, this delivery format may assist with improved interaction and absorption once the compound reaches systemic circulation.
Core Areas of Support
Methylation pathways
Homocysteine metabolism
Cardiovascular health
Cellular hydration and osmotic balance
Cognitive biochemical pathways
Energy metabolism
Liver function
Suggested Use
Take 2 capsules daily with meals, or as directed by a qualified healthcare professional.
Product Features
1,000 mg Trimethylglycine per serving
Liposomal delivery system from sunflower lecithin
Vegetarian capsules
Non-GMO
No unnecessary fillers
Manufactured in the USA in cGMP-certified facilities
Functional Overview
Homocysteine Metabolism
TMG participates in the betaine-homocysteine methyltransferase (BHMT) pathway, donating a methyl group to convert homocysteine into methionine. This process supports normal cardiovascular and endothelial function.
SAMe & Methionine Cycle Support
Through its role in remethylation, TMG contributes to the regeneration of methionine, which is required to form S-adenosylmethionine (SAMe). SAMe acts as a universal methyl donor involved in neurotransmitter production, cellular repair processes, and metabolic regulation.
Epigenetic Regulation
DNA methylation is a mechanism that helps regulate gene expression. By contributing methyl groups, TMG supports the biochemical processes associated with normal epigenetic function.
Liver & Lipid Metabolism
Methylation is involved in phosphatidylcholine synthesis, a component necessary for normal lipid transport in the liver. Through this pathway, TMG supports healthy hepatic fat metabolism.
Cellular Osmoprotection
TMG also functions as an osmolyte — a compound that helps maintain cellular fluid balance during physiological stress. This role supports structural stability and metabolic efficiency in various tissues.
Cognitive & Neurotransmitter Support
Methylation contributes to the synthesis of neurotransmitters such as dopamine, serotonin, and norepinephrine. By supporting methyl group availability, TMG helps maintain the biochemical environment required for balanced neural communication.
Ingredients
Active Ingredient
- Trimethylglycine (TMG) – 1,000 mg per serving
Other Ingredients
- Vegetable cellulose (capsule)
- Microcrystalline cellulose
- Maltodextrin
- Phospholipid complex (sunflower lecithin, phosphatidylcholine)
- Silicon dioxide
- Vegetable stearate
Quality & Transparency
All GenuinePurity® products are manufactured in the United States in facilities operating under cGMP standards. Independent laboratory testing helps ensure consistency and product integrity.
97-Day Money-Back Guarantee
Your purchase is protected by a 100% satisfaction guarantee. If you are not fully satisfied, you may return up to two opened bottles along with any unopened units within 97 days for a full refund of the purchase price.
Frequently Asked Questions
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How should I take it?
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Take two capsules daily with food for ongoing support.
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What does Liposomal TMG support?
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This formula is designed to support:
- Healthy methylation activity
- Homocysteine balance
- Cardiovascular function
- Liver metabolism
- Energy production
- Cognitive biochemical pathways
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When will my order arrive?
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Most orders arrive within 3–5 business days, depending on location.
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Who can I contact with questions?
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Customer support is available toll-free at 1-866-968-6643 (North America) or 1-778-770-2961 (International). Live chat is available daily from 6 a.m. to 6 p.m. Pacific Time, excluding holidays.
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